♦ Les publications de l'équipe

Année 2022

Resistance Training of Inspiratory Muscles After Coronary Artery Disease May Improve Obstructive Sleep Apnea in Outpatient Cardiac Rehabilitation: RICAOS Study.
Labeix P, Berger M, Zellag A, Garcin A, Barthelemy JC, Roche F, Hupin D.
Front Physiol. 2022 Mar 3;13:846532. doi: 10.3389/fphys.2022.846532. eCollection 2022.

Leukoaraiosis and Gray Matter Volume Alteration in Older Adults: The PROOF Study.
Celle S, Boutet C, Annweiler C, Ceresetti R, Pichot V, Barthélémy JC, Roche F.
Front Neurosci. 2022 Jan 13;15:747569. doi: 10.3389/fnins.2021.747569. eCollection 2021

Association between nocturnal heart rate variability and incident cardiovascular disease events: The HypnoLaus population-based study.
Berger M, Pichot V, Solelhac G, Marques-Vidal P, Haba-Rubio J, Vollenweider P, Waeber G, Preisig M, Barthélémy JC, Roche F, Heinzer R.
Heart Rhythm. 2022 Apr;19(4):632-639. doi: 10.1016/j.hrthm.2021.11.033. Epub 2021 Dec 2

Association Between Physical Activity, Quadriceps Muscle Performance, and Biological Characteristics of Very Old Men and Women.
Varesco G, Coudy-Gandilhon C, Lapole T, Decourt A, Gueugneau M, Barthélémy JC, Roche F, Bechet D, Féasson L, Rozand V.
J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):47-54. doi: 10.1093/gerona/glab239.

Targeting autonomic nervous system as a biomarker of well-ageing in the prevention of stroke.
Barthelemy JC, Pichot V, Hupin D, Berger M, Celle S, Mouhli L, Bäck M, Lacour JR, Roche F.
Front Aging Neurosci. 2022 Sep 15;14:969352. doi: 10.3389/fnagi.2022.969352. eCollection 2022.

Premature atrial contractions: A predictor of atrial fibrillation and a relevant marker of atrial cardiomyopathy.
Guichard JB, Guasch E, Roche F, Da Costa A, Mont L.
Front Physiol. 2022 Oct 24;13:971691. doi: 10.3389/fphys.2022.971691. eCollection 2022.

Clinical autonomic nervous system laboratories in Europe: A joint survey of the European Academy of Neurology and the European Federation of Autonomic Societies: A joint survey of the European Academy of Neurology and the European Federation of Autonomic Societies.
Habek M, Leys F, Krbot Skoric M, Reis Carneiro D, Calandra-Buonaura G, Camaradou J, Chiaro G, Cortelli P, Falup-Pecurariu C, Granata R, Guaraldi P, Helbok R, Hilz MJ, Iodice V, Jordan J, Kaal ECA, Kamondi A, Pavy Le Traon A, Rocha I, Sellner J, Senard JM, Terkelsen A, Wenning GK, Berger T, Thijs RD, Struhal W, Fanciulli A; Collaborators of the European Network of Clinical ANS laboratories.
Eur J Neurol. 2022 Dec;29(12):3633-3646. doi: 10.1111/ene.15538. Epub 2022 Sep 20

Effects of intermittent hypoxia with thrombin in an in vitro model of human brain endothelial cells and their impact on PAR-1/PAR-3 cleavage.
Zolotoff C, Puech C, Roche F, Perek N.
Sci Rep. 2022 Jul 19;12(1):12305. doi: 10.1038/s41598-022-15592-x.

Association between depressive symptoms and long-term heart rate variability in older women: Findings from a population-based cohort.
Rouch I, Edjolo A, Celle S, Pichot V, Laurent B, Borg C, Dorey JM, Roche F.
J Affect Disord. 2022 May 15;305:151-158. doi: 10.1016/j.jad.2022.02.053. Epub 2022 Feb 25.

Année 2021

Longer-term effects of supervised physical activity on obstructive sleep apnea and subsequent health consequences.
Berger M, Barthélémy JC, Garet M, Raffin J, Labeix P, Roche F, Hupin D.
Scand J Med Sci Sports. 2021 Jul;31(7):1534-1544. doi: 10.1111/sms.13961.

Association Between Physical Activity, Quadriceps Muscle Performance, and Biological Characteristics of Very Old Men and Women.
Varesco G, Coudy-Gandilhon C, Lapole T, Decourt A, Gueugneau M, Barthélémy JC, Roche F, Bechet D, Féasson L, Rozand V.
J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):47-54. doi: 10.1093/gerona/glab239.

Muscle Proteomic and Transcriptomic Profiling of Healthy Aging and Metabolic Syndrome in Men. n L, Béchet D.
Gueugneau M, Coudy-Gandilhon C, Chambon C, Verney J, Taillandier D, Combaret L, Polge C, Walrand S, Roche F, Barthélémy JC, Féasso
Int J Mol Sci. 2021 Apr 19;22(8):4205. doi: 10.3390/ijms22084205.

Insulin Resistance and Type 2 Diabetes in Asymptomatic Obstructive Sleep Apnea: Results of the PROOF Cohort Study After 7 Years of Follow-Up.
Vacelet L, Hupin D, Pichot V, Celle S, Court-Fortune I, Thomas T, Garcin A, Barthélémy JC, Gozal D, Roche F.
Front Physiol. 2021 Jul 28;12:650758. doi: 10.3389/fphys.2021.650758. eCollection 2021.

Social Marketing Intervention to Engage Older Adults in Balance Workshops for Fall Prevention: A Multicenter Quasi-Experimental Protocol Study.
Goethals L, Barth N, Hupin D, Chapoton B, Guyot J, Celarier T, Roche F, Gallopel-Morvan K, Bongue B.
Front Public Health. 2021 Jul 14;9:614119. doi: 10.3389/fpubh.2021.614119. eCollection 2021.

Obstructive Sleep Apnea, Hypercoagulability, and the Blood-Brain Barrier.
Zolotoff C, Bertoletti L, Gozal D, Mismetti V, Flandrin P, Roche F, Perek N.
J Clin Med. 2021 Jul 14;10(14):3099. doi: 10.3390/jcm10143099.PMID: 34300265 Free PMC article. Review.

Obstructive sleep apnea/hypopnea syndrome phenotypes after night sleep recordings: how to get to precision medicine in 2021.
Roche F, Mouhli L, Pichot V, Celle S.
Sleep. 2021 Jul 9;44(7):zsab154. doi: 10.1093/sleep/zsab154.

Associations between physical activity types and multi-domain cognitive decline in older adults from the Three-city cohort.
Dupré C, Helmer C, Bongue B, Dartigues JF, Roche F, Berr C, Carrière I.
PLoS One. 2021 Jun 1;16(6):e0252500. doi: 10.1371/journal.pone.0252500. eCollection 2021.



Année 2020

Sera of elderly obstructive sleep apnea patients alter blood-brain barrier integrity in vitro: a pilot study.
Voirin AC, Celle S, Perek N, Roche F.
Sci Rep. 2020 Jul 9;10(1):11309. doi: 10.1038/s41598-020-68374-8.

Causal analyses to study autonomic regulation during acute head-out water immersion, head-down tilt and supine position.
Corbier C, Chouchou F, Roche F, Barthélémy JC, Pichot V.
Exp Physiol. 2020 Aug;105(8):1216-1222. doi: 10.1113/EP088640.

Electronic cigarettes and health with special focus on cardiovascular effects: position paper of the European Association of Preventive Cardiology (EAPC).
Kavousi M, Pisinger C, Barthelemy JC, Smedt D, Koskinas K, Marques-Vidal P, Panagiotakos D, Prescott EB, Tiberi M, Vassiliou VS, Løchen ML
Eur J Prev Cardiol. 2020 Jul 29:2047487320941993. doi: 10.1177/2047487320941993.

Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly.
Raberin A, Connes P, Barthélémy JC, Robert P, Celle S, Hupin D, Faes C, Rytz C, Roche F, Pialoux V
Oxid Med Cell Longev. 2020 Jun 19;2020:1315471. doi: 10.1155/2020/1315471. eCollection 2020.

Intermittent Hypoxia and Its Impact on Nrf2/HIF-1? Expression and ABC Transporters: An in Vitro Human Blood-Brain Barrier Model Study.
Zolotoff C, Voirin AC, Puech C, Roche F, Perek N.
Cell Physiol Biochem. 2020 Dec 17;54(6):1231-1248. doi: 10.33594/000000311.

Sleep apnoea and endothelial dysfunction: An individual patient data meta-analysis.
Bironneau V, Tamisier R, Trzepizur W, Andriantsitohaina R, Berger M, Goupil F, Joyeux-Faure M, Jullian-Desayes I, Launois S, Le Vaillant M, Martinez MC, Roche F, Pépin JL,Bironneau V, Tamisier R, Trzepizur W, Andriantsitohaina R, Berger M, Goupil F, Joyeux-Faure M, Jullian-Desayes I, Launois S, Le Vaillant M, Martinez MC, Roche F, Pépin JL, Gagnadoux F.
Sleep Med Rev. 2020 Aug;52:101309. doi: 10.1016/j.smrv.2020.101309. Epub 2020 Mar 13.

Inflammatory stress induced by a combination of cytokines (IL-6, IL-17, TNF-?) leads to a loss of integrity on bEnd.3 endothelial cells in vitro BBB model.
Voirin AC, Perek N, Roche F.
Brain Res. 2020 Mar 1;1730:146647. doi: 10.1016/j.brainres.2020.146647. Epub 2020 Jan 3

Care through cohort studies: sociological survey of the PROOF cohort study on vascular and cognitive aging.
Savall A, Charles R, Bujon T, Roche F, Barthélémy JC, Rabeharisoa V.
J Public Health (Oxf). 2020 Nov 23;42(4):740-747. doi: 10.1093/pubmed/fdz187.

Structural skin changes in elderly people investigated by reflectance confocal microscopy.
Cinotti E, Bovi C, Tonini G, Labeille B, Heusèle C, Nizard C, Schnebert S, Aubailly S, Barthélémy JC, Cambazard F, Cevenini G, Tognetti L, Cartocci A, Rubegni P, Perrot JL.
J Eur Acad Dermatol Venereol. 2020 Nov;34(11):2652-2658. doi: 10.1111/jdv.16466. Epub 2020 Aug 2. PMID: 32294278

Année 2019

Muscle loss associated changes of oxylipin signatures during biological aging: an exploratory study from the PROOF cohort.
Dalle C, Ostermann AI, Konrad T, Coudy-Gandilhon C, Decourt A, Barthélémy JC, Roche F, Féasson L, Mazur A, Béchet D, Schebb NH, Gladine C.
J Gerontol A Biol Sci Med Sci. 2019 Apr 23;74(5):608-615. doi: 10.1093/gerona/gly187. PMID: 30137216 .

Factors Influencing Adherence to Auto-CPAP: An Observational Monocentric Study Comparing Patients With and Without Cardiovascular Diseases.
Nsair A, Hupin D, Chomette S, Barthélémy JC, Roche F.
Front Neurol. 2019 Aug 2;10:801. doi: 10.3389/fneur.2019.00801. eCollection 2019.

Autonomic cardiovascular adaptations to acute head-out water immersion, head-down tilt and supine position.
Chouchou F, Pichot V, Costes F, Guillot M, Barthélémy JC, Bertoletti L, Roche F.
Eur J Appl Physiol. 2020 Feb;120(2):337-347. doi: 10.1007/s00421-019-04278-4. Epub 2019 Dec 7.

Magnesium transport and homeostasis-related gene expression in skeletal muscle of young and old adults: analysis of the transcriptomic data from the PROOF cohort Study.
Coudy-Gandilhon C, Gueugneau M, Taillandier D, Combaret L, Polge C, Roche F, Barthélémy JC, Féasson L, Maier JA, Mazur A, Béchet D.
Magnes Res. 2019 Aug 1;32(3):72-82. doi: 10.1684/mrh.2019.0458.

Sex-specific maternofetal innate immune responses triggered by group B Streptococci.
Allard MJ, Giraud A, Segura M, Sebire G.
Sci Rep. 2019 Jun 13;9(1):8587.

Effect of exercise training on heart rate variability in patients with obstructive sleep apnea: A randomized controlled trial.
Berger M, Raffin J, Pichot V, Hupin D, Garet M, Labeix P, Costes F, Barthélémy JC, Roche F.
Scand J Med Sci Sports. 2019 May 2.

The impact of severe late-effects after 12 Gy fractionated total body irradiation and allogeneic stem cell transplantation for childhood leukemia (1988-2010).
Freycon F, Casagranda L, Trombert-Paviot B.
Pediatr Hematol Oncol. 2019 Mar;36(2):86-102.

Exercise Frequency Determines Heart Rate Variability Gains in Older People: A Meta-Analysis and Meta-Regression.
Raffin J, Barthélémy JC, Dupré C, Pichot V, Berger M, Féasson L, Busso T, Da Costa A, Colvez A, Montuy-Coquard C, Bouvier R, Bongue B, Roche F, Hupin D.
Sports Med. 2019 May;49(5):719-729.

Interest of follow-up of recommendations over a period of 6 months for elderly subjects who have been screened for frailty.
Jugand R, Gonthier R, Martinez L, Dupré C, Célarier T.
Geriatr Psychol Neuropsychiatr Vieil. 2019 Jun 1;17(2):145-152.

Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study.
Hupin D, Raffin J, Barth N, Berger M, Garet M, Stampone K, Celle S, Pichot V, Bongue B, Barthelemy JC, Roche F.
Front Public Health. 2019 Mar 19;7:51.

Does obstructive sleep apnea affect exercise capacity and the hemodynamic response to exercise? An individual patient data and aggregate meta-analysis.
Berger M, Kline CE, Cepeda FX, Rizzi CF, Chapelle C, Laporte S, Hupin D, Raffin J, Costes F, Hargens TA, Barthélémy JC, Roche F.
Sleep Med Rev. 2019 Jun;45:42-53.

Assessing pain in the postoperative period: Analgesia Nociception IndexTMvs pupillometry.
Charier D, Vogler MC, Zantour D, Pichot V, Martins-Baltar A, Courbon M, Roche F, Vassal F, Molliex S.
Br J Anaesth. 2019 Jan 26. pii: S0007-0912(18)31383-7.

Autonomic maturation from birth to 2 years: normative values.
Patural H, Pichot V, Flori S, Giraud A, Franco P, Pladys P, Beuchée A, Roche F, Barthelemy JC.
Heliyon. 2019 Mar 7;5(3):e01300.

Outlier removal methods for skewed data: impact on age-specific high-sensitive cardiac troponin T 99th percentiles.
Monneret D, Gellerstedt M, Roche F, Bonnefont-Rousselot D.
Clin Chem Lab Med. 2019 Mar 12.

How the insula speaks to the heart: Cardiac responses to insular stimulation in humans.
Chouchou F, Mauguière F, Vallayer O, Catenoix H, Isnard J, Montavont A, Jung J, Pichot V, Rheims S, Mazzola L.
Hum Brain Mapp. 2019 Jun 15;40(9):2611-2622.

Volunteer and career French firefighters: Cardiovascular risk factors and cardiovascular risk assessment.
Savall A, Charles R, Bertholon A, Gramont B, Trombert B, Barthélémy JC, Roche F.
Eur J Prev Cardiol. 2019 Feb 5:2047487319827463.

Early polysomnographic characteristics associated with neurocognitive development at 36 months of age.
Franco P, Guyon A, Stagnara C, Flori S, Bat-Pitault F, Lin JS, Patural H, Plancoulaine S.
Sleep Med. 2019 Jan 5. pii: S1389-9457(19)30001-2.

Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects.
Meier-Girard D, Delgado-Eckert E, Schaffner E, Schindler C, Künzli N, Adam M, Pichot V, Kronenberg F, Imboden M, Frey U, Probst-Hensch N.
Environ Int. 2019 Apr;125:107-116.

Case report: Staphylococcus aureus endocarditis in 2 premature newborns.
Duperril M, Rapin S, Vuillard C, Rayet I, Patural H.
Medicine (Baltimore). 2019 Jan;98(1):e13549.

Dysautonomia in Childhood Cancer Survivors: A Widely Underestimated Risk.
Berger C, Casagranda L, Pichot V, Trombert-Paviot B, Faure-Conter C, Freycon C, Isfan F, Guichard I, Durieu I, Garcin A, Roche F, Patural H.
J Adolesc Young Adult Oncol. 2019 Feb;8(1):9-17.

Arterial stiffness alteration and obstructive sleep apnea in an elderly cohort free of cardiovascular event history: the PROOF cohort study.
Sforza E, Millasseau S, Hupin D, Barthélémy JC, Roche F.
Sleep Breath. 2019 Mar;23(1):201-208.

Année 2018

Mononucleosis: A Possible Cause of Idiopathic Hypersomnia.
Sforza E, Hupin D, Roche F.
Front Neurol. 2018 Oct 31;9:922.

Benefits of supervised community physical activity in obstructive sleep apnoea.
Berger M, Barthélémy JC, Hupin D, Raffin J, Dupré C, Labeix P, Costes F, Gaspoz JM, Roche F.
Eur Respir J. 2018 Nov 22;52(5).

[Discrepancies and overdiagnosis in breast cancer organized screening. A "methodology" systematic review].
Gocko X, Leclerq M, Plotton C.
Rev Epidemiol Sante Publique. 2018 Nov;66(6):395-403.

Autonomic cardiac regulation after general anesthesia in children.
Venet T, Pichot V, Charier D, Scalabre A, Patural H.
Paediatr Anaesth. 2018 Oct;28(10):881-887.

Ankle pressure and ankle brachial index after heavy load incremental exercise.
Godet R, Bruneau A, Vielle B, Vincent F, Le Tourneau T, Carre F, Hupin D, Hamel JF, Abraham P, Henni S.
Scand J Med Sci Sports. 2018 Nov;28(11):2459.

Muscle loss associated changes of oxylipin signatures during biological aging: an exploratory study from the PROOF cohort.
Dalle C, Ostermann AI, Konrad T, Coudy-Gandilhon C, Decourt A, Barthélémy JC, Roche F, Féasson L, Mazur A, Béchet D, Schebb NH, Gladine C.
J Gerontol A Biol Sci Med Sci. 2018 Aug 23.

Volunteer and Career French Firefighters With High Cardiovascular Risk: Epidemiology and Exercise Tests.
Savall A, Charles R, Binazet J, Frey F, Trombert B, Fontana L, Barthélémy JC, Pelissier C.
J Occup Environ Med. 2018 Oct;60(10):e548-e553.

Obstructive Sleep Apnea in Cardiac Rehabilitation Patients.
Hupin D, Pichot V, Berger M, Sforza E, Raffin J, Lietar C, Poyraz E, Maudoux D, Barthelemy JC, Roche F.
J Clin Sleep Med. 2018 Jul 15;14(7):1119-1126.

Performance analysis of walking of 10,000 regular users of a connected activity tracker.
Le Hello C, Trombert B, Morel A, Chieh A, Brouard B, Boissier C.
J Med Vasc. 2018 Jul;43(4):231-237.

Sleep apnoea in the asymptomatic elderly: a real issue for the brain?
Celle S, Boutet C, Annweiler C, Barthélémy JC, Roche F.
Eur Respir J. 2018 Jun 14;51(6). pii: 1702450.

Post-exercise ankle blood pressure and ankle to brachial index after heavy load bicycle exercise.
Godet R, Bruneau A, Vielle B, Vincent F, Le Tourneau T, Carre F, Hupin D, Hamel JF, Abraham P, Henni S.
Scand J Med Sci Sports. 2018 Oct;28(10):2144-2152.

Fecundity and Quality of Life of Women Treated for Solid Childhood Tumors Between 1948 and 1992 in France.
Thouvenin-Doulet S, Berger C, Casagranda L, Oberlin O, Marec-Berard P, Pacquement H, Guibout C, Freycon C, N'Guyen TD, Bondiau PY, Laprie A, Berchery D, El-Fayech C, Trombert-Paviot B, de Vathaire F.
J Adolesc Young Adult Oncol. 2018 Aug;7(4):415-423.

Contextual modulation of autonomic pain reactivity.
Fauchon C, Pichot V, Faillenot I, Pommier B, Garcia-Larrea L, Peyron R, Chouchou F.
Auton Neurosci. 2018 Jul;212:28-31.

Pain and emotion as predictive factors of interoception in fibromyalgia.
Borg C, Chouchou F, Dayot-Gorlero J, Zimmerman P, Maudoux D, Laurent B, Michael GA.
J Pain Res. 2018 Apr 19;11:823-835.

Exercise electrocardiogram in middle-aged and older leisure time sportsmen: 100 exercise tests would be enough to identify one silent myocardial ischemia at risk for cardiac event.
Hupin D, Edouard P, Oriol M, Laukkanen J, Abraham P, Doutreleau S, Guy JM, Carré F, Barthélémy JC, Roche F, Chatard JC.
Int J Cardiol. 2018 Apr 15;257:16-23.

Use of Vitamin K Antagonists and Brain Morphological Changes in Older Adults: An Exposed/Unexposed Voxel-Based Morphometric Study.
Brangier A, Celle S, Roche F, Beauchet O, Ferland G, Annweiler C.
Dement Geriatr Cogn Disord. 2018;45(1-2):18-26.

Objective assessment of induced acute pain in neonatology with the Newborn Infant Parasympathetic Evaluation index.
Cremillieux C, Makhlouf A, Pichot V, Trombert B, Patural H.
Eur J Pain. 2018 Jul;22(6):1071-1079.

Heart rate variability and baroreflex sensitivity in bilateral lung transplant recipients.
Fontolliet T, Gianella P, Pichot V, Barthélémy JC, Gasche-Soccal P, Ferretti G, Lador F.
Clin Physiol Funct Imaging. 2018 Sep;38(5):872-880.

Année 2017

Role of Perinatal Inflammation in Neonatal Arterial Ischemic Stroke.
Giraud A, Guiraut C, Chevin M, Chabrier S, Sébire G.
Front Neurol. 2017 Nov 16;8:612.

Predictive performance of four frailty screening tools in community-dwelling elderly.
Bongue B, Buisson A, Dupre C, Beland F, Gonthier R, Crawford-Achour É.
BMC Geriatr. 2017 Nov 10;17(1):262.

Long-lasting active lifestyle and successful cognitive aging in a healthy elderly population: The PROOF cohort.
Saint Martin M, Sforza E, Barthélémy JC, Roche F, Lefèvre P, Liénard G, Thomas-Anterion C; PROOF group study.
Rev Neurol (Paris). 2017 Dec;173(10):637-644.

Predictors of Discharge Destinations and Three-Month Evolution of Patients Initially Hospitalized in a Cognitive Behavioral Unit.
Pongan E, Dorey JM, Krolak-Salmon P, Federico D, Sellier C, Auguste N, Fabre F, Laurent B, Trombert-Paviot B, Rouch I.
J Alzheimers Dis. 2017;60(4):1259-1266.

Does an observer's empathy influence my pain? Effect of perceived empathetic or unempathetic support on a pain test.
Fauchon C, Faillenot I, Perrin AM, Borg C, Pichot V, Chouchou F, Garcia-Larrea L, Peyron R.
Eur J Neurosci. 2017 Nov;46(10):2629-2637.

Maturation of arousals during day and night in infants with non-smoking and smoking mothers.
Gillioen B, Plancoulaine S, Montemitro E, Flori S, Lin JS, Guyon A, Stagnara C, Bat-Pitault F, Patural H, Gustin MP, Franco P.
Early Hum Dev. 2017 Dec;115:46-50.

Hydralazine is a Suitable Mimetic Agent of Hypoxia to Study the Impact of Hypoxic Stress on In Vitro Blood-Brain Barrier Model.
Chatard M, Puech C, Perek N, Roche F.
Cell Physiol Biochem. 2017;42(4):1592-1602.

Assessing Pain Using the Variation Coefficient of Pupillary Diameter.
Charier DJ, Zantour D, Pichot V, Chouchou F, Barthelemy JM, Roche F, Molliex SB.
J Pain. 2017 Nov;18(11):1346-1353.

The neural bases of ictal tachycardia in temporal lobe seizures.
Chouchou F, Bouet R, Pichot V, Catenoix H, Mauguière F, Jung J.
Clin Neurophysiol. 2017 Sep;128(9):1810-1819.

Long-Term Follow-up Consultation After Childhood Cancer in the Rhône-Alpes Region of France: Feedback From Adult Survivors and Their General Practitioners.
Berger C, Casagranda L, Faure-Conter C, Freycon C, Isfan F, Robles A, Trombert-Paviot B, Guichard I, Durieu I, Cathebras P.
J Adolesc Young Adult Oncol. 2017 Dec;6(4):524-534.

Blood parameters of preterm neonates: postnatal evolution according to gestational age.
Roudil P, Vasselon C, Trombert-Paviot B, Berger C, Patural H.
Int J Lab Hematol. 2017 Jun;39(3):317-328.

Atrial fibrillation in cancer patients: Hindsight, insight and foresight.
Mery B, Guichard JB, Guy JB, Vallard A, Barthelemy JC, Da Costa A, Magné N, Bertoletti L.
Int J Cardiol. 2017 Aug 1;240:196-202.

A 7-year follow-up study of obstructive sleep apnoea in healthy elderly: The PROOF cohort study.
Sforza E, Hupin D, Pichot V, Barthélémy JC, Roche F.
Respirology. 2017 Jul;22(5):1007-1014.

Early features associated with the neurocognitive development at 36 months of age: the AuBE study.
Plancoulaine S, Stagnara C, Flori S, Bat-Pitault F, Lin JS, Patural H, Franco P.
Sleep Med. 2017 Feb;30:222-228.

Altered sleep architecture during the first months of life in infants born to depressed mothers.
Bat-Pitault F, Sesso G, Deruelle C, Flori S, Porcher-Guinet V, Stagnara C, Guyon A, Plancoulaine S, Adrien J, Da Fonseca D, Patural H, Franco P.
Sleep Med. 2017 Feb;30:195-203.

Sleep Trajectories Among Pregnant Women and the Impact on Outcomes: A Population-Based Cohort Study.
Plancoulaine S, Flori S, Bat-Pitault F, Patural H, Lin JS, Franco P.
Matern Child Health J. 2017 May;21(5):1139-1146.

Année 2016

Is there an association between altered baroreceptor sensitivity and obstructive sleep apnoea in the healthy elderly?.
Sforza E, Martin MS, Barthélémy JC, Roche F.
ERJ Open Res. 2016 Sep 28;2(3).

Risk factors of osteoporosis in healthy elderly with unrecognized obstructive sleep apnea: role of physical activity.
Sforza E, Saint Martin M, Thomas T, Collet P, Garet M, Barthélémy JC, Roche F.
Sleep Med. 2016 Jun;22:25-32.

Supra-Epiglottic Upper Airway Volume in Elderly Patients with Obstructive Sleep Apnea Hypopnea Syndrome.
Boutet C, Abdirahman Mohamed Moussa S, Celle S, Laurent B, Barthélémy JC, Barral FG, Roche F.
PLoS One. 2016 Jun 23;11(6):e0157720.

Hippocampus volume and subjective sleepiness in older people with sleep-disordered breathing: a preliminary report.
Sforza E, Celle S, Saint-Martin M, Barthélémy JC, Roche F.
J Sleep Res. 2016 Apr;25(2):190-3.

Mood disorders in healthy elderly with obstructive sleep apnea: a gender effect.
Sforza E, Saint Martin M, Barthélémy JC, Roche F.
Sleep Med. 2016 Mar;19:57-62.

Incidental findings on brain magnetic resonance imaging in the elderly:the PROOF study.
Boutet C, Vassal F, Celle S, Schneider FC, Barthélémy JC, Laurent B, Barral FG, Roche F.
Brain Imaging Behav. 2016 Feb 3.

Sleep disruptions increase arterial stiffness.
Chouchou F, Pichot V, Celle S, Barthélémy JC, Gosse P, Roche F.
Int J Cardiol. 2016 Jan 15;203:744-5. doi: 10.1016/j.ijcard.2015.11.010.

Physical activity for older adults: Even a little is good!
Hupin D, Roche F, Oriol M, Garet M, Pichot V, Gremeaux V, Chatard JC, Achour E, Berger M, Gaspoz JM, Feasson L, Barthelemy JC, Edouard P.
Ann Phys Rehabil Med. 2016 Sep;59S:e58.

Identification and comparison of the predictors of maximal inspiratory force and handgrip in a healthy elderly population. The proof study.
Costes F, Celle S, Garet M, Kossovsky M, Roche F, Barthélémy JC.
Clin Nutr. 2016 Aug;35(4):963-7.

Sleep-related autonomic overactivity in a general elderly population and its relationship to cardiovascular regulation.
Crawford-Achour E, Roche F(2,), Pichot V, Celle S, Barthélémy JC, Chouchou F.
Heart Vessels. 2016 Jan;31(1):46-51.

Année 2015

Prevalence and determinants of subjective sleepiness in healthy elderly with unrecognized obstructive sleep apnea.
Sforza E, Pichot V, Martin MS, Barthélémy JC, Roche F.
Sleep Med. 2015 Aug;16(8):981-6.

Echocardiographic Findings in Healthy Elderly People with Unrecognized Sleep Disordered Breathing.
Sforza E, Sabri M, DaCosta A, Isaaz K, Barthélémy JC, Roche F.
J Clin Sleep Med. 2015 Sep 15;11(9):975-80.

Protective Effect of Long-Term CPAP Therapy on Cognitive Performance in Elderly Patients with Severe OSA: The PROOF Study.
Crawford-Achour E, Dauphinot V, Martin MS, Tardy M, Gonthier R, Barthelemy JC, Roche F.
J Clin Sleep Med. 2015 Apr 15;11(5):519-24. doi: 10.5664/jcsm.4694.

Sudomotor function and obesity-related risk factors in an elderly healthy population: The PROOF-Synapse Study.
Hupin D, Pichot V, Celle S, Maudoux D, Calvet JH, Barthélémy JC, Roche F.
Int J Cardiol. 2015;186:247-9. doi: 10.1016/j.ijcard.2015.03.273.

Skeletal muscle lipid content and oxidative activity in relation to muscle fiber type in aging and metabolic syndrome.
Gueugneau M, Coudy-Gandilhon C, Théron L, Meunier B, Barboiron C, Combaret L, Taillandier D, Polge C, Attaix D, Picard B, Verney J, Roche F, Féasson L, Barthélémy JC, Béchet D.
J Gerontol A Biol Sci Med Sci. 2015 May;70(5):566-76.

Association of body fat composition and obstructive sleep apnea in the elderly: A longitudinal study.
Saint Martin M, Roche F, Thomas T, Collet P, Barthélémy JC, Sforza E.
121. Obesity (Silver Spring). 2015 Jul;23(7):1511-6.

Subjective sleep and cognitive complaints in 65 year old subjects: a significant association. The PROOF cohort.
Tardy M, Gonthier R, Barthelemy JC, Roche F, Crawford-Achour E.
J Nutr Health Aging. 2015 Apr;19(4):424-30.

Sleep breathing disorders and cognitive function in the elderly: an 8-year follow-up study. the proof-synapse cohort.
Martin MS, Sforza E, Roche F, Barthélémy JC, Thomas-Anterion C; PROOF study group.
Sleep. 2015 Feb 1;38(2):179-87.

Eight-year parallel change in baroreflex sensitivity and memory function in a sample of healthy older adults.
Saint Martin M, Roche F, Thomas-Anterion C, Barthélémy JC, Sforza E; PROgnostic OF cardiovascular and cerebrovascular events study group.
J Am Geriatr Soc. 2015 Feb;63(2):270-5.

Bariatric surgery associated with percutaneous auricular vagal stimulation: A new prospective treatment on weight loss.
Sforza E, Sabri M, DaCosta A, Isaaz K, Barthélémy JC, Roche F.
J Clin Sleep Med. 2015 Mar 27. pii: jc-00437-14. [Epub ahead of print]

Effects of gravitational acceleration on cardiovascular autonomic control in resting humans.
Fontolliet T, Pichot V, Antonutto G, Bonjour J, Capelli C, Tam E, Barthélémy JC, Ferretti G.
Eur J Appl Physiol. 2015 Feb 14. [Epub ahead of print]

Modeling of performance and ANS activity for predicting future responses to training.
Chalencon S, Pichot V, Roche F, Lacour JR, Garet M, Connes P, Barthélémy JC, Busso T.
Eur J Appl Physiol. 2015 Mar;115(3):589-96.

Skeletal muscle lipid content and oxidative activity in relation to muscle fiber type in aging and metabolic syndrome.
Gueugneau M, Coudy-Gandilhon C, Théron L, Meunier B, Barboiron C, Combaret L, Taillandier D, Polge C, Attaix D, Picard B, Verney J, Roche F, Féasson L, Barthélémy JC, Béchet D.
J Gerontol A Biol Sci Med Sci. 2015 May;70(5):566-76.

Protective Effect of Long-Term CPAP Therapy on Cognitive Performance in Elderly Patients with Severe OSA: The PROOF Study.
Crawford-Achour E, Dauphinot V, Martin MS, Tardy M, Gonthier R, Barthelemy JC, Roche F.
J Clin Sleep Med. 2015;11:519-524.

Sleep Breathing Disorders and Cognitive Function in the Elderly: An 8-Year Follow-up Study.
Saint Martin M, Sforza E, Roche F, Barthélémy JC, Thomas-Anterion C; on behalf of the PROOF study group.
The Proof-Synapse Cohort. Sleep. 2015;38:179-87. [5,100]

Sudomotor function and obesity-related risk factors in an elderly healthy population: The PROOF-Synapse Study.
Hupin D, Pichot V, Celle S, Maudoux D, Calvet JH, Barthélémy JC, Roche F.
Int J Cardiol. 2015;186:247-249.

Subjective sleep and cognitive complaints in 65 year old subjects: a significant association.
Tardy M, Gonthier R, Barthelemy JC, Roche F, Crawford-Achour E.
The proof cohort. J Nutr Health Aging. 2015;19(4):424-30.

ECG-derived respiration: A promising tool for sleep-disordered breathing diagnosis in chronic heart failure patients.
Pichot V, Chouchou F, Pepin JL, Tamisier R, Lévy P, Court-Fortune I, Sforza E, Barthélémy JC, Roche F.
Int J Cardiol. 2015 Mar 18;186:7-9.

Echocardiographic Findings in Healthy Elderly People with Unrecognized Sleep Disordered Breathing.
Sforza E, Sabri M, DaCosta A, Isaaz K, Barthélémy JC, Roche F.
J Clin Sleep Med. 2015 Mar 27. pii: jc-00437-14. [Epub ahead of print]

Eight-year parallel change in baroreflex sensitivity and memory function in a sample of healthy older adults.
Saint Martin M, Roche F, Thomas-Anterion C, Barthélémy JC, Sforza E, and the PROgnostic OF cardiovascular and cerebrovascular events study group.
J Am Geriatr Soc. 2015;63:270-5.

Année 2014

Sleep-related breathing disorders and gait variability: a cross-sectional preliminary study.
Celle S, Annweiler C, Camicioli R, Barthélémy JC, Roche F, Beauchet O.
BMC Pulm Med. 2014 Aug 23;14(1):140. doi: 10.1186/1471-2466-14-140.

Sleep-related autonomic overactivity in a general elderly population and its relationship to cardiovascular regulation.
Crawford-Achour E, Roche F, Pichot V, Celle S, Barthélémy JC, Chouchou F.
Heart Vessels. 2014 Aug 24. [Epub ahead of print]

Association of self-reported sleep and hypertension in non-insomniac elderly subjects.
Sforza E, Saint Martin M, Barthelemy JC, Roche F.
J Clin Sleep Med. 2014 Sep 15;10(9):965-71. doi: 10.5664/jcsm.4026.

Prediction of Pulmonary Restriction from Forced Vital Capacity in Elderly is Similar Using GLI and ERS Equations.
Bruel Tronchon N, Frappé E, Chomette Ballereau S, Barthélémy JC, Costes F.
Lung. 2014 Oct;192(5):775-9. doi: 10.1007/s00408-014-9627-0. Epub 2014 Jul 27.

Skeletal Muscle Lipid Content and Oxidative Activity in Relation to Muscle Fiber Type in Aging and Metabolic Syndrome.
Gueugneau M, Coudy-Gandilhon C, Théron L, Meunier B, Barboiron C, Combaret L, Taillandier D, Polge C, Attaix D, Picard B, Verney J, Roche F, Féasson L, Barthélémy JC, Béchet D.
J Gerontol A Biol Sci Med Sci. 2014 Jun 17. pii: glu086. [Epub ahead of print]

Metabolic Syndrome is Associated with Poor Memory and Executive Performance in Elderly Community Residents: The PROOF Study.
Rouch I, Trombert B, Kossowsky MP, Laurent B, Celle S, Ntougou Assoumou G, Roche F, Barthelemy JC.
Am J Geriatr Psychiatry. 2014 Jan 25. pii: S1064-7481(14)00032-3. doi: 10.1016/j.jagp.2014.01.005. [Epub ahead of print]

Leukoaraiosis and ambulatory blood pressure load in a healthy elderly cohort study: the PROOF study.
Avet J, Pichot V, Barthélémy JC, Laurent B, Garcin A, Roche F, Celle S.
Int J Cardiol. 2014 Mar 1;172(1):59-63. doi: 10.1016/j.ijcard.2013.11.052. Epub 2013 Nov 23.

Cardiac sympathetic modulation in response to apneas/hypopneas through heart rate variability analysis.
Chouchou F, Pichot V, Barthélémy JC, Bastuji H, Roche F.
PLoS One. 2014 Jan 22;9(1):e86434. doi: 10.1371/journal.pone.0086434. eCollection 2014.

[Autonomic regulation and bradycardia during the neonatal period].
Patural H, Flori S, Pichot V, Barthelemy JC, Roche F.
Arch Pediatr. 2014 Feb;21(2):226-30. doi: 10.1016/j.arcped.2013.10.001. Epub 2013 Nov 26. French.

Sleep perception in non-insomniac healthy elderly: a 3-year longitudinal study.
Martin MS, Sforza E, Barthélémy JC, Thomas-Anterion C, Roche F.
Rejuvenation Res. 2014 Feb;17(1):11-8. doi: 10.1089/rej.2013.1457.

Higher gait variability is associated with decreased parietal gray matter volume among healthy older adults.
Beauchet O, Annweiler C, Celle S, Bartha R, Barthélémy JC, Roche F.
Brain Topogr. 2014 Mar;27(2):293-5. doi: 10.1007/s10548-013-0293-y. Epub 2013 May 17.

Année 2013

Baroreflex sensitivity, vascular risk factors, and cognitive function in a healthy elderly population: the PROOF cohort. Saint Martin M, Sforza E, Thomas-Anterion C, Barthélémy JC, Roche F; PROOF Study Group. J Am Geriatr Soc. 2013 Dec;61(12):2096-102. doi: 10.1111/jgs.12548. Epub 2013 Nov 26.

Obstructive sleep apnea is associated with preserved bone mineral density in healthy elderly subjects. Sforza E, Thomas T, Barthélémy JC, Collet P, Roche F. Sleep. 2013 Oct 1;36(10):1509-15. doi: 10.5665/sleep.3046.

Impaired baroreflex sensitivity and the risks of new-onset ambulatory hypertension, in an elderly population-based study. Dauphinot V, Kossovsky MP, Gueyffier F, Pichot V, Gosse P, Roche F, Barthélémy JC. Int J Cardiol. 2013 Oct 9;168(4):4010-4. doi: 10.1016/j.ijcard.2013.06.080. Epub 2013 Jul 17.

Association between severe obstructive sleep apnea and incident arterial hypertension in the older people population. Guillot M, Sforza E, Achour-Crawford E, Maudoux D, Saint-Martin M, Barthélémy JC, Roche F. Sleep Med. 2013 Sep;14(9):838-42. doi: 10.1016/j.sleep.2013.05.002. Epub 2013 Jul 3.

Sympathetic overactivity due to sleep fragmentation is associated with elevated diurnal systolic blood pressure in healthy elderly subjects: the PROOF-SYNAPSE study. Chouchou F, Pichot V, Pépin JL, Tamisier R, Celle S, Maudoux D, Garcin A, Lévy P, Barthélémy JC, Roche F; PROOF Study Group. Eur Heart J. 2013 Jul;34(28):2122-31, 2131a. doi: 10.1093/eurheartj/eht208. Epub 2013 Jun 11.

Relation of central fat mass to obstructive sleep apnea in the elderly. Degache F, Sforza E, Dauphinot V, Celle S, Garcin A, Collet P, Pichot V, Barthélémy JC, Roche F; PROOF Study Group. Sleep. 2013 Apr 1;36(4):501-7. doi: 10.5665/sleep.2532.

[Chronic cough in the elderly is associated with expiratory flow limitation]. Frappé E, Gautier-Guillot M, Barthélémy JC, Maudoux D, Roche F, Costes F. Rev Mal Respir. 2013 Mar;30(3):179-86. doi: 10.1016/j.rmr.2012.09.020. Epub 2012 Dec 13. French.

Carotid artery atherosclerosis and sleep disordered breathing in healthy elderly subjects: the Synapse cohort. Sforza E, Boissier C, Martin MS, Feasson S, Barthélémy JC, Roche F. Sleep Med. 2013 Jan;14(1):66-70. doi: 10.1016/j.sleep.2012.08.016. Epub 2012 Nov 3.

Thoracic impedance, in association with oximetry, in a multi-modal ECG Holter system is useful for screening sleep disordered breathing. Chouchou F, Poupard L, Philippe C, Court-Fortune I, Barthélémy JC, Roche F. Int J Cardiol. 2013 Feb 10;163(1):100-2. doi: 10.1016/j.ijcard.2012.06.082. Epub 2012 Jul 16. No abstract available.

Année 2012

A model for the training effects in swimming demonstrates a strong relationship between parasympathetic activity, performance and index of fatigue. Chalencon S, Busso T, Lacour JR, Garet M, Pichot V, Connes P, Gabel CP, Roche F, Barthélémy JC. PLoS One. 2012;7(12):e52636. doi: 10.1371/journal.pone.0052636. Epub 2012 Dec 20.

Diabetes, impaired fasting glucose, and cognitive decline in a population of elderly community residents. Rouch I, Roche F, Dauphinot V, Laurent B, Antérion CT, Celle S, Krolak-Salmon P, Barthélémy JC. Aging Clin Exp Res. 2012 Aug;24(4):377-83.

Premature atrial contractions in the general population: frequency and risk factors. Conen D, Adam M, Roche F, Barthelemy JC, Felber Dietrich D, Imboden M, Künzli N, von Eckardstein A, Regenass S, Hornemann T, Rochat T, Gaspoz JM, Probst-Hensch N, Carballo D. Circulation. 2012 Nov 6;126(19):2302-8. doi: 10.1161/Circulation AHA.112.112300. Epub 2012 Oct 9.

Association between ambulatory 24-hour blood pressure levels and brain volume reduction: a cross-sectional elderly population-based study. Celle S, Annweiler C, Pichot V, Bartha R, Barthélémy JC, Roche F, Beauchet O. Hypertension. 2012 Nov;60(5):1324-31. doi: 10.1161/HypertensionAHA.112.193409. Epub 2012 Oct 8.

Depressive symptoms and autonomic nervous system dysfunction in an elderly population-based study: the PROOF study. Dauphinot V, Rouch I, Kossovsky MP, Pichot V, Dorey JM, Krolak-Salmon P, Laurent B, Roche F, Barthélémy JC. J Affect Disord. 2012 Dec 20;143(1-3):153-9. doi: 10.1016/j.jad.2012.05.045. Epub 2012 Aug 19.

Does subjective sleep affect cognitive function in healthy elderly subjects? The Proof cohort. Saint Martin M, Sforza E, Barthélémy JC, Thomas-Anterion C, Roche F. Sleep Med. 2012 Oct;13(9):1146-52. doi: 10.1016/j.sleep.2012.06.021. Epub 2012 Aug 6.

Successful aging: how to improve its occurrence in the elderly? Crawford-Achour E, Castro-Lionard K, Tardy M, Trombert-Paviot B, Barthélémy JC, Gonthier R. Geriatr Psychol Neuropsychiatr Vieil. 2012 Jun 1;10(2):207-214.

Heart rate variability in association with frequent use of household sprays and scented products in SAPALDIA. Mehta AJ, Adam M, Schaffner E, Barthélémy JC, Carballo D, Gaspoz JM, Rochat T, Schindler C, Schwartz J, Zock JP, Künzli N, Probst-Hensch N; SAPALDIA Team. Environ Health Perspect. 2012 Jul;120(7):958-64. doi: 10.1289/ehp.1104567. Epub 2012 Apr 10.

At 68 years, unrecognised sleep apnoea is associated with elevated ambulatory blood pressure. Roche F, Pépin JL, Achour-Crawford E, Tamisier R, Pichot V, Celle S, Maudoux D, Chouchou F, Ntougou-Assoumou HG, Lévy P, Barthélémy JC; PROOF Study Group. Eur Respir J. 2012 Sep;40(3):649-56. Epub 2012 Apr 20.

Occupational exposure to dusts, gases, and fumes and incidence of chronic obstructive pulmonary disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults. Mehta AJ, Miedinger D, Keidel D, Bettschart R, Bircher A, Bridevaux PO, Curjuric I, Kromhout H, Rochat T, Rothe T, Russi EW, Schikowski T, Schindler C, Schwartz J, Turk A, Vermeulen R, Probst-Hensch N, Künzli N; SAPALDIA Team. Am J Respir Crit Care Med. 2012 Jun 15;185(12):1292-300. doi: 10.1164/rccm.201110-1917OC. Epub 2012 Apr 6.

A 3-year longitudinal study of sleep disordered breathing in the elderly. Sforza E, Gauthier M, Crawford-Achour E, Pichot V, Maudoux D, Barthélémy JC, Roche F. Eur Respir J. 2012 Sep;40(3):665-72. doi: 10.1183/09031936.00133011. Epub 2012 Mar 9.

Alteration of baroreflex sensitivity in the elderly: the relationship with metabolic syndrome components. Assoumou HG, Bertholon F, Barthélémy JC, Pichot V, Celle S, Gosse P, Gaspoz JM, Roche F. Int J Cardiol. 2012 Mar 8;155(2):333-5. doi: 10.1016/j.ijcard.2011.12.050. Epub 2012 Jan 10. No abstract available.

Heart rate increment in the diagnosis of obstructive sleep apnoea in an older population. Sforza E, Chouchou F, Pichot V, Barthélémy JC, Roche F. Sleep Med. 2012 Jan;13(1):21-8. doi: 10.1016/j.sleep.2011.04.011. Epub 2011 Nov 21.

Autonomic activation during sleep and new-onset ambulatory hypertension in the elderly. Dauphinot V, Barthélémy JC, Pichot V, Celle S, Sforza E, Achour-Crawford E, Gosse P, Roche F. Int J Cardiol. 2012 Feb 23;155(1):155-9. doi: 10.1016/j.ijcard.2011.10.097. Epub 2011 Nov 9.

Obstructive sleep apnea and the metabolic syndrome in an elderly healthy population: the SYNAPSE cohort. Assoumou HG, Gaspoz JM, Sforza E, Pichot V, Celle S, Maudoux D, Kossovsky M, Chouchou F, Barthelemy JC, Roche F. Sleep Breath. 2012 Sep;16(3):895-902. doi: 10.1007/s11325-011-0593-y. Epub 2011 Sep 18.

Année 2011

Obesity-related autonomic nervous system disorders are best associated with body fat mass index, a new indicator. Ntougou Assoumou HG, Pichot V, Barthelemy JC, Dauphinot V, Celle S, Collet P, Gaspoz JM, Roche F. Int J Cardiol. 2011 Nov 17;153(1):111-3. doi: 10.1016/j.ijcard.2011.09.031. Epub 2011 Oct 2. No abstract available.

Pulse transit time in screening sleep disordered breathing in an elderly population: the PROOF-SYNAPSE study. Chouchou F, Sforza E, Celle S, Pichot V, Maudoux D, Garcin A, Barthélémy JC, Roche F; PROOF Study Group. Sleep. 2011 Aug 1;34(8):1051-9. doi: 10.5665/SLEEP.1160.

Aortic root size and sleep apnea in elderly: a cohort study. Achour EC, Roche F, Romeyer-Bouchard C, Mayaud N, Bisch L, Isaaz K, Dacosta A, Barthelemy JC. Int J Cardiol. 2011 Aug 18;151(1):101-2. doi: 10.1016/j.ijcard.2011.06.006. Epub 2011 Jun 23. No abstract available.

Autonomic dysfunction in 2009 pandemic influenza A (H1N1) virus-related infection: a pediatric comparative study. Mattéi J, Teyssier G, Pichot V, Barthélémy JC, Achour E, Pillet S, Bourlet T, Patural H. Auton Neurosci. 2011 Jul 5;162(1-2):77-83. doi: 10.1016/j.autneu.2011.03.003. Epub 2011 Apr 8.

Level of physical activity at the age of 65 predicts successful aging seven years later: the PROOF study. Achour EC, Barthelemy JC, Lionard KC, Trombert B, Lacour JR, Thomas-Anterion C, Gonthier R, Garet M, Roche F. Rejuvenation Res. 2011 Apr;14(2):215-21. doi: 10.1089/rej.2010.1101. Epub 2011 Mar 31.

Increased waist circumference is the component of metabolic syndrome the most strongly associated with elevated C-reactive protein in elderly. Assoumou HG, Barthelemy JC, Garet M, Dauphinot V, Celle S, Pichot V, Kossovsky M, Gaspoz JM, Roche F. Metab Syndr Relat Disord. 2011 Aug;9(4):281-5. doi: 10.1089/met.2010.0115. Epub 2011 Mar 25.

Can maintaining cognitive function at 65 years old predict successful ageing 6 years later? The PROOF study. Castro-Lionard K, Thomas-Antérion C, Crawford-Achour E, Rouch I, Trombert-Paviot B, Barthélémy JC, Laurent B, Roche F, Gonthier R. Age Ageing. 2011 Mar;40(2):259-65. doi: 10.1093/ageing/afq174. Epub 2011 Jan 20.

Is the Berlin questionnaire a useful tool to diagnose obstructive sleep apnea in the elderly? Sforza E, Chouchou F, Pichot V, Herrmann F, Barthélémy JC, Roche F. Sleep Med. 2011 Feb;12(2):142-6. doi: 10.1016/j.sleep.2010.09.004. Epub 2011 Jan 11.

Use of high-frequency peak in spectral analysis of heart rate increment to improve screening of obstructive sleep apnoea. Poupard L, Court-Fortune I, Pichot V, Chouchou F, Barthélémy JC, Roche F. Sleep Breath. 2011 Dec;15(4):837-43. doi: 10.1007/s11325-010-0446-0. Epub 2010 Nov 21.

Sex differences in obstructive sleep apnoea in an elderly French population. Sforza E, Chouchou F, Collet P, Pichot V, Barthélémy JC, Roche F. Eur Respir J. 2011 May;37(5):1137-43. doi: 10.1183/09031936.00043210. Epub 2010 Sep 3.

Determinants of change in airway reactivity over 11 years in the SAPALDIA population study. Curjuric I, Zemp E, Dratva J, Ackermann-Liebrich U, Bridevaux PO, Bettschart RW, Brutsche M, Frey M, Gerbase MW, Knöpfli B, Künzli N, Pons M, Schwartz J, Schindler C, Rochat T; SAPALDIA team. Eur Respir J. 2011 Mar;37(3):492-500. doi: 10.1183/09031936.00188609. Epub 2010 Jun 7.

Année 2010

Metabolic syndrome and short-term and long-term heart rate variability in elderly free of clinical cardiovascular disease: the PROOF study. Assoumou HG, Pichot V, Barthelemy JC, Dauphinot V, Celle S, Gosse P, Kossovsky M, Gaspoz JM, Roche F. Rejuvenation Res. 2010 Dec;13(6):653-63. doi: 10.1089/rej.2010.1019. Epub 2010 Sep 6.

Decrease in gait variability while counting backward: a marker of "magnet effect"? Beauchet O, Allali G, Poujol L, Barthelemy JC, Roche F, Annweiler C. J Neural Transm. 2010 Oct;117(10):1171-6. doi: 10.1007/s00702-010-0463-y. Epub 2010 Aug 31.

Autonomic nervous system activity is independently associated with the risk of shift in the non-dipper blood pressure pattern. Dauphinot V, Gosse P, Kossovsky MP, Schott AM, Rouch I, Pichot V, Gaspoz JM, Roche F, Barthelemy JC. Hypertens Res. 2010 Oct;33(10):1032-7. doi: 10.1038/hr.2010.130. Epub 2010 Jul 29.

[Vasovagal syncope in children]. Teyssier G, Patural H, Barthelemy JC. Arch Pediatr. 2010 Jun;17(6):995-6. doi: 10.1016/S0929-693X(10)70216-5. French. No abstract available.

Prevalence of clinical and ambulatory hypertension in a population of 65-year-olds: the PROOF study. Gosse P, Dauphinot V, Roche F, Pichot V, Celle S, Barthelemy JC. J Clin Hypertens (Greenwich). 2010 Mar;12(3):160-5. doi: 10.1111/j.1751-7176.2009.00235.x.

Autonomic dysfunction with early respiratory syncytial virus-related infection. Stock C, Teyssier G, Pichot V, Goffaux P, Barthelemy JC, Patural H. Auton Neurosci. 2010 Aug 25;156(1-2):90-5. doi: 10.1016/j.autneu.2010.03.012. Epub 2010 Apr 18.

Cognitive function and sleep related breathing disorders in a healthy elderly population: the SYNAPSE study. Sforza E, Roche F, Thomas-Anterion C, Kerleroux J, Beauchet O, Celle S, Maudoux D, Pichot V, Laurent B, Barthélémy JC. Sleep. 2010 Apr;33(4):515-21.

Is tidal expiratory flow limitation predictive of sleep-related disorders in the elderly? Guillot M, Costes F, Sforza E, Maudoux D, Bertoletti L, Barthélémy JC, Roche F. Eur Respir J. 2010 Oct;36(4):842-8. doi: 10.1183/09031936.00078009. Epub 2010 Apr 8.

Association between ambulatory 24-hour blood pressure levels and cognitive performance: a cross-sectional elderly population-based study. Beauchet O, Herrmann FR, Annweiler C, Kerlerouch J, Gosse P, Pichot V, Celle S, Roche F, Barthelemy JC. Rejuvenation Res. 2010 Feb;13(1):39-46. doi: 10.1089/rej.2009.0878.

HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction. Curjuric I, Imboden M, Schindler C, Downs SH, Hersberger M, Liu SL, Matyas G, Russi EW, Schwartz J, Thun GA, Postma DS, Rochat T, Probst-Hensch NM; SAPALDIA team. Eur Respir J. 2010 Mar;35(3):505-14. doi: 10.1183/09031936.00044309. Erratum in: Eur Respir J. 2010 Nov;36(5):1225.

Prevalence and clinical correlates of restless legs syndrome in an elderly French population: the synapse study. Celle S, Roche F, Kerleroux J, Thomas-Anterion C, Laurent B, Rouch I, Pichot V, Barthélémy JC, Sforza E. J Gerontol A Biol Sci Med Sci. 2010 Feb;65(2):167-73. doi: 10.1093/gerona/glp161. Epub 2009 Nov 13.

Relationship of cardiac involvement with arterial stiffness in a general population of 65-year-olds in the PROOF study. Gosse P, Pichot V, Guilhot M, Dauphinot V, Da Costa A, Barthelemy JC, Roche F. J Hypertens. 2010 Feb;28(2):389-94. doi: 10.1097/HJH.0b013e328333d1a4.

Lack of specific gray matter alterations in restless legs syndrome in elderly subjects. Celle S, Roche F, Peyron R, Faillenot I, Laurent B, Pichot V, Barthélémy JC, Sforza E. J Neurol. 2010 Mar;257(3):344-8. doi: 10.1007/s00415-009-5320-2. Epub 2009 Sep 22.

Année 2009

Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect. Imboden M, Schwartz J, Schindler C, Curjuric I, Berger W, Liu SL, Russi EW, Ackermann-Liebrich U, Rochat T, Probst-Hensch NM; SAPALDIA Team. Environ Health Perspect. 2009 Sep;117(9):1420-7. doi: 10.1289/ehp.0800430. Epub 2009 May 26.

C-reactive protein implications in new-onset hypertension in a healthy population initially aged 65 years: the Proof study. Dauphinot V, Roche F, Kossovsky MP, Schott AM, Pichot V, Gaspoz JM, Gosse P, Barthelemy JC. J Hypertens. 2009 Apr;27(4):736-43. doi: 10.1097/HJH.0b013e328326f801.

Traffic-related air pollution correlates with adult-onset asthma among never-smokers. Künzli N, Bridevaux PO, Liu LJ, Garcia-Esteban R, Schindler C, Gerbase MW, Sunyer J, Keidel D, Rochat T; Swiss Cohort Study on Air Pollution and Lung Diseases in Adults. Thorax. 2009 Aug;64(8):664-70. doi: 10.1136/thx.2008.110031. Epub 2009 Apr 8.

Infant botulism intoxication and autonomic nervous system dysfunction. Patural H, Goffaux P, Paricio C, Emeriaud G, Teyssier G, Barthelemy JC, Pichot V, Roche F. Anaerobe. 2009 Oct;15(5):197-200. doi: 10.1016/j.anaerobe.2009.03.004. Epub 2009 Mar 25.

Pulmonary hypertension does not affect the autonomic nervous system dysfunction of sickle cell disease. Inamo J, Connes P, Barthélémy JC, Dan V, Coates T, Loko G. Am J Hematol. 2009 May;84(5):311-2. doi: 10.1002/ajh.21377. No abstract available.

Association between C-reactive protein and unrecognised sleep-disordered breathing in the elderly. Roche F, Gaspoz JM, Pichot V, Picard-Kossovsky M, Maudoux D, Garcin A, Celle S, Sforza E, Barthélémy JC; PROOF and SYNAPSE Study Groups. Eur Respir J. 2009 Apr;33(4):797-803. doi: 10.1183/09031936.00023208. Epub 2009 Feb 12.

Obstructive sleep apnoea/hypopnea influences high-density lipoprotein cholesterol in the elderly. Roche F, Sforza E, Pichot V, Maudoux D, Garcin A, Celle S, Picard-Kossovsky M, Gaspoz JM, Barthélémy JC; PROOF Study Group. Sleep Med. 2009 Sep;10(8):882-6. doi: 10.1016/j.sleep.2008.07.017. Epub 2009 Feb 5.

Improvements in PM10 exposure and reduced rates of respiratory symptoms in a cohort of Swiss adults (SAPALDIA). Schindler C, Keidel D, Gerbase MW, Zemp E, Bettschart R, Brändli O, Brutsche MH, Burdet L, Karrer W, Knöpfli B, Pons M, Rapp R, Bayer-Oglesby L, Künzli N, Schwartz J, Liu LJ, Ackermann-Liebrich U, Rochat T; SAPALDIA Team. Am J Respir Crit Care Med. 2009 Apr 1;179(7):579-87. doi: 10.1164/rccm.200803-388OC. Epub 2009 Jan 16.

Undiagnosed sleep-related breathing disorders are associated with focal brainstem atrophy in the elderly. Celle S, Peyron R, Faillenot I, Pichot V, Alabdullah M, Gaspoz JM, Laurent B, Barthélémy JC, Roche F. Hum Brain Mapp. 2009 Jul;30(7):2090-7. doi: 10.1002/hbm.20650.

Année 2008

Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers. Probst-Hensch NM, Imboden M, Felber Dietrich D, Barthélemy JC, Ackermann-Liebrich U, Berger W, Gaspoz JM, Schwartz J. Environ Health Perspect. 2008 Nov;116(11):1494-9. doi: 10.1289/ehp.11402. Epub 2008 Jul 18.

Differences in heart rate variability associated with long-term exposure to NO2. Felber Dietrich D, Gemperli A, Gaspoz JM, Schindler C, Liu LJ, Gold DR, Schwartz J, Rochat T, Barthélémy JC, Pons M, Roche F, Probst Hensch NM, Bridevaux PO, Gerbase MW, Neu U, Ackermann-Liebrich U; SAPALDIA Team. Environ Health Perspect. 2008 Oct;116(10):1357-61. doi: 10.1289/ehp.11377. Epub 2008 Jun 20.

Cognitive complaints, neuropsychological performance and affective disorders in elderly community residents. Rouch I, Anterion CT, Dauphinot V, Kerleroux J, Roche F, Barthelemy JC, Laurent B. Disabil Rehabil. 2008;30(23):1794-802. doi: 10.1080/09638280701667825.

Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study. Felber Dietrich D, Ackermann-Liebrich U, Schindler C, Barthélémy JC, Brändli O, Gold DR, Knöpfli B, Probst-Hensch NM, Roche F, Tschopp JM, von Eckardstein A, Gaspoz JM; Sapaldia team. Eur J Appl Physiol. 2008 Oct;104(3):557-65. doi: 10.1007/s00421-008-0800-0. Epub 2008 Jul 3.

[Normal and changed heart rate maturation of the neonate]. Patural H, Teyssier G, Pichot V, Barthelemy JC. Arch Pediatr. 2008 Jun;15(5):614-6. doi: 10.1016/S0929-693X(08)71851-7. French. No abstract available.

Autonomic cardiac control of very preterm newborns: a prolonged dysfunction. Patural H, Pichot V, Jaziri F, Teyssier G, Gaspoz JM, Roche F, Barthelemy JC. Early Hum Dev. 2008 Oct;84(10):681-7. doi: 10.1016/j.earlhumdev.2008.04.010. Epub 2008 Jun 16.

Components of arterial stiffness in a population of 65-year-old subjects: PROOF study. Gosse P, Roche F, Dauphinot V, Maudoux D, Pichot V, Barthelemy JC. J Hypertens. 2008 Jun;26(6):1138-46. doi: 10.1097/HJH.0b013e3282fa142b.

Année 2007

Autonomic nervous system activity and decline as prognostic indicators of cardiovascular and cerebrovascular events: the 'PROOF' Study. Study design and population sample. Associations with sleep-related breathing disorders: the 'SYNAPSE' Study. Barthélémy JC, Pichot V, Dauphinot V, Celle S, Laurent B, Garcin A, Maudoux D, Kerleroux J, Lacour JR, Kossovsky M, Gaspoz JM, Roche F. Neuroepidemiology. 2007;29(1-2):18-28.

Monitoring of ventilation during the early part of cardiopulmonary exercise testing: the first step to detect central sleep apnoea in chronic heart failure. Roche F, Maudoux D, Jamon Y, Barthelemy JC. Sleep Med. 2008 May;9(4):411-7. Epub 2007 Aug 29.

Autonomic nervous system activity in premature and full-term infants from theoretical term to 7 years. De Rogalski Landrot I, Roche F, Pichot V, Teyssier G, Gaspoz JM, Barthelemy JC, Patural H. Auton Neurosci. 2007 Oct 30;136(1-2):105-9. Epub 2007 Jun 7.

Cardiac variability and heart-rate increment as a marker of sleep fragmentation in patients with a sleep disorder: a preliminary study. Sforza E, Pichot V, Cervena K, Barthélémy JC, Roche F. Sleep. 2007 Jan;30(1):43-51.

Analysis of the interbeat interval increment to detect obstructive sleep apnoea/hypopnoea. Roche F, Celle S, Pichot V, Barthélémy JC, Sforza E. Eur Respir J. 2007 Jun;29(6):1206-11. Epub 2007 Feb 14.